Long-read sequencing typically provide reads lengths >15 Kbases help resolve challenging genomic regions such as complex structural variants or regions that contain highly repetitive elements. Long reads have also provide better genome assemblies over coming the difficulties in mapping repetitive regions or regions of high GC content that lack coverage with short-read technologies.

The Genomics Core has an outsourcing arrangement with the Genome Technology Access Center at the McDonnell Genome Institute at Washington University. Long read sequencing services are available using either a PacBio Revio or Oxford Nanopore Promethion24. Our core will handle all submission arrangements, ship samples, and manage payments for MU researchers. Data will be made available through our own data distribution pipeline and stored according to GTC data retention policies.

Contact Nathan Bivens (bivensn@missouri.edu), Genomics Core director, to learn more about this service.